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Sodium Starch Glycolate

SSG Sodium Starch Glycolate
Grades Type A (Ph. Eur.)
CAS NO 9063-38-1
HS Code 29420090
Molecular Formula C2H4O3·xNa·x
Applications Oral pharmaceuticals as a disintegrant in capsule and
tablet formulations
Packing Type 25 Kgs Corrugated boxes / Fiber Drum
Loss on drying Max 10.0% Ph. Eur., NF, JP
pH 5.5 - 7.5 Ph. Eur., NF, JP
Residue on Ethanol max. 3.0% In house method
The raw materials, manufacturing process and product do not contain any of the solvents listed in Residual Solvents (Ph. Eur. <5.4>, USP<467>) except for ethanol limited to < 3.0%

Sodium starch glycolate is the sodium salt of carboxymethyl ether. Starch glycolates are of rice, potato, wheat or corn origin. Sodium starch glycoate is a white to off-white, tasteless, odorless, relatively free flowing powder.

Sodium starch glycolate is used as a pharmaceutical grade dissolution excipient for tablets and capsules. Sodium starch glycolate absorbs water rapidly, resulting in swelling which leads to rapid disintegration of tablets and granules. It is used as a disintegrant, a suspending agent and as a gelling agent. Without a disintegrant, tablets may not dissolve appropriately and may effect the amount of active ingredient absorbed, thereby decreasing effectiveness.

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